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It is a mock commercial for "C.S.I. Ziplock Body Bags" and zip lock bags for dismembered body parts. Investigators are at a crime scene in a kitchen and two women speak to camera about the Ziplock bags.
Jay Leno's guests: Holly Hunter, Jeff Gordon and music by Keith Urban.
Jay's guests: Pamela Anderson, Erykah Badu, Corbin Maxey and Brandon Molale.
Hazardous Material workers are going through mail looking for anthrax. Jay breaks in and blows off white powder to get to the Sports Illustrated swimsuit issue.